| Gene Information | |
|---|---|
| Gene Name | DCK |
| Organism | Homo sapiens (Human) |
| Gene Length | 260 |
| Protein Names | Deoxycytidine kinase (dCK) (EC 2.7.1.74) (Deoxyadenosine kinase) (EC 2.7.1.76) (Deoxyguanosine kinase) (EC 2.7.1.113) |
| Target Name | deoxycytidine kinase |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000156136 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P27707 |
| Gene Card | DCK |
| Uniprot ID | P27707 |
| Pfam | PF01712 |
| In ASD | no |
| Allosteric Prediction | yes (0.727144013) |
| Ortholog in Animals | Alpaca_ DCK ( ortholog_one2one ) Dog_ DCK ( ortholog_one2one ) GuineaPig_ DCK ( ortholog_one2one ) Macaque_ DCK ( ortholog_one2one ) Mouse_ Dck ( ortholog_one2one ) Rat_ Dck ( ortholog_one2one ) Rabbit_ DCK ( ortholog_one2one ) |
| Ohnologs | DGUOK |
| Paralogs | NDUFA10, TK2, DGUOK |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1P5Z (X-ray 1.60A ) 1P60 (X-ray 1.96A ) 1P61 (X-ray 2.21A ) 1P62 (X-ray 1.90A ) 2A2Z (X-ray 3.02A ) 2A30 (X-ray 3.02A ) 2A7Q (X-ray 2.55A ) 2NO0 (X-ray 1.80A ) 2NO1 (X-ray 1.91A ) 2NO6 (X-ray 1.90A ) 2NO7 (X-ray 1.70A ) 2NO9 (X-ray 2.15A ) 2NOA (X-ray 1.80A ) 2QRN (X-ray 3.40A ) 2QRO (X-ray 3.45A ) 2ZI3 (X-ray 2.30A ) 2ZI4 (X-ray 2.10A ) 2ZI5 (X-ray 1.77A ) 2ZI6 (X-ray 1.77A ) 2ZI7 (X-ray 1.97A ) 2ZI9 (X-ray 2.51A ) 2ZIA (X-ray 1.80A ) 3HP1 (X-ray 2.31A ) 3IPX (X-ray 2.00A ) 3IPY (X-ray 2.54A ) 3KFX (X-ray 1.96A ) 3MJR (X-ray 2.10A ) 3QEJ (X-ray 2.49A ) 3QEN (X-ray 2.00A ) 3QEO (X-ray 1.90A ) 4JLJ (X-ray 2.00A ) 4JLK (X-ray 1.89A ) 4JLM (X-ray 2.18A ) 4JLN (X-ray 2.15A ) 4KCG (X-ray 2.09A ) 4L5B (X-ray 1.94A ) 4Q18 (X-ray 2.00A ) 4Q19 (X-ray 2.09A ) 4Q1A (X-ray 1.90A ) 4Q1B (X-ray 2.15A ) 4Q1C (X-ray 2.00A ) 4Q1D (X-ray 2.00A ) 4Q1E (X-ray 1.85A ) 4Q1F (X-ray 2.10A ) 5MQJ (X-ray 3.70A ) 5MQL (X-ray 3.25A ) 5MQT (X-ray 3.20A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:9342341}. |
| Mouse PG classification | NA |
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