| Gene Information | |
|---|---|
| Gene Name | MGR |
| Organism | Homo sapiens (Human) |
| Gene Length | 618 |
| Protein Names | Grainyhead-like protein 1 homolog (Mammalian grainyhead) (NH32) (Transcription factor CP2-like 2) (Transcription factor LBP-32) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9NZI5 |
| Gene Card | GRHL1 |
| Uniprot ID | Q9NZI5 |
| Pfam | PF04516 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Isoform 1 is highly expressed in brain, pancreas, tonsil, placenta and kidney. Isoform 2 is highly expressed in brain and liver. Expressed at very low levels in non-steroidogenic cells. {ECO:0000269|PubMed:10644752, ECO:0000269|PubMed:12175488}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5MPF (X-ray 2.92A ) 5MPH (X-ray 2.34A ) 5MPI (X-ray 2.35A ) |
| DBSNP | rs16867256 rs2303920 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:18288204}. |
| Mouse PG classification | NA |
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