| Gene Information | |
|---|---|
| Gene Name | OASL |
| Organism | Homo sapiens (Human) |
| Gene Length | 514 |
| Protein Names | 2'-5'-oligoadenylate synthase-like protein (2'-5'-OAS-related protein) (2'-5'-OAS-RP) (59 kDa 2'-5'-oligoadenylate synthase-like protein) (Thyroid receptor-interacting protein 14) (TR-interacting protein 14) (TRIP-14) (p59 OASL) (p59OASL) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000135114 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q15646 |
| Gene Card | OASL |
| Uniprot ID | Q15646 |
| Pfam | PF10421; PF00240 |
| In ASD | no |
| Allosteric Prediction | no (-0.740082634) |
| Ortholog in Animals | Alpaca_ OASL ( ortholog_one2one ) Dog_ OASL ( ortholog_one2one ) GuineaPig_ OASL ( ortholog_one2one ) Macaque_ OASL ( ortholog_one2one ) Mouse_ Oasl1 ( ortholog_one2one ) Pig_ OASL ( ortholog_one2one ) Rat_ Oasl ( ortholog_one2one ) Rabbit_ OASL ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | OAS2, OAS3, OAS1 |
| Tissue | bone.marrow, stomach |
| Tissue Specificity | Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 1WH3 (NMR - ) 4XQ7 (X-ray 1.60A ) |
| DBSNP | rs35249920 |
| Subcellular location [CC] | [Isoform p56]: Nucleus, nucleolus. Cytoplasm.; [Isoform p30]: Cytoplasm. |
| Mouse PG classification | NA |
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