| Gene Information | |
|---|---|
| Gene Name | ESRRG |
| Organism | Homo sapiens (Human) |
| Gene Length | 458 |
| Protein Names | Estrogen-related receptor gamma (ERR gamma-2) (Estrogen receptor-related protein 3) (Nuclear receptor subfamily 3 group B member 3) |
| Target Name | estrogen-related receptor gamma |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000196482 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P62508 |
| Gene Card | ESRRG |
| Uniprot ID | P62508 |
| Pfam | PF00104; PF00105 |
| In ASD | no |
| Allosteric Prediction | yes (0.478952196) |
| Ortholog in Animals | Alpaca_ ESRRG ( ortholog_one2one ) Dog_ ESRRG ( ortholog_one2one ) GuineaPig_ ESRRG ( ortholog_one2one ) Macaque_ ESRRG ( ortholog_one2one ) Mouse_ Esrrg ( ortholog_one2one ) Pig_ ESRRG ( ortholog_one2one ) Rat_ Esrrg ( ortholog_one2one ) Rabbit_ ESRRG ( ortholog_one2one ) |
| Ohnologs | ESR1, NR3C1, ESRRB, ESR2, ESRRA |
| Paralogs | NR3C1, ESRRA, ESR1, AR, ESR2, PGR, NR3C2, ESRRB |
| Tissue | NA |
| Tissue Specificity | Expressed in the heart, kidney, brain, lung, bone marrow, adrenal gland, trachea, spinal cord and thyroid gland. {ECO:0000269|PubMed:14651967, ECO:0000269|PubMed:9676434}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | 1KV6 (X-ray 2.70A ) 1TFC (X-ray 2.40A ) 1VJB (X-ray 3.20A ) 2E2R (X-ray 1.60A ) 2EWP (X-ray 2.30A ) 2GP7 (X-ray 2.45A ) 2GPO (X-ray 1.95A ) 2GPP (X-ray 2.60A ) 2GPU (X-ray 1.70A ) 2GPV (X-ray 2.85A ) 2P7A (X-ray 2.30A ) 2P7G (X-ray 2.10A ) 2P7Z (X-ray 2.50A ) 2ZAS (X-ray 2.00A ) 2ZBS (X-ray 1.80A ) 2ZKC (X-ray 1.70A ) 5YSO (X-ray 2.50A ) 6A6K (X-ray 2.90A ) 6I61 (X-ray 1.65A ) 6I62 (X-ray 1.65A ) 6I63 (X-ray 2.23A ) 6I64 (X-ray 1.91A ) 6I65 (X-ray 1.50A ) 6I66 (X-ray 1.60A ) 6I67 (X-ray 1.75A ) 6K3N (X-ray 1.97A ) 6KNR (X-ray 2.80A ) 6XXC (X-ray 1.30A ) 6XY5 (X-ray 1.30A ) 6Y18 (X-ray 1.30A ) 6Y1D (X-ray 1.38A ) 6Y3W (X-ray 1.34A ) 6Y58 (X-ray 1.90A ) |
| DBSNP | rs11572693 |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
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