| Gene Information | |
|---|---|
| Gene Name | PPP1R42 |
| Organism | Homo sapiens (Human) |
| Gene Length | 309 |
| Protein Names | Protein phosphatase 1 regulatory subunit 42 (Leucine-rich repeat-containing protein 67) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000178125 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q7Z4L9 |
| Gene Card | PPP1R42 |
| Uniprot ID | Q7Z4L9 |
| Pfam | PF12799 |
| In ASD | no |
| Allosteric Prediction | no (-1.480160045) |
| Ortholog in Animals | Alpaca_ PPP1R42 ( ortholog_one2one ) Dog_ TCF24 ( ortholog_one2one ) Macaque_ PPP1R42 ( ortholog_one2one ) Mouse_ Ppp1r42 ( ortholog_one2one ) Pig_ PPP1R42 ( ortholog_one2one ) Rat_ Ppp1r42 ( ortholog_one2one ) Rabbit_ PPP1R42 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | LRRC43, DNAAF11, DRC3, LRRCC1, LRRC9, LRRC46, DNAAF1, LRRC49, CEP97, LRRC23, LRRC61, LRRIQ3, LRGUK |
| Tissue | testis |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003133(Rat);0.046429(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q8R1Z4}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q8R1Z4}. Note=Colocalizes with alpha tubulin to the manchette of developing spermatids. Detected to nuclear rim in pachytene spermatocytes. Detected at nuclear surface, opposite the acrosome in elongating spermatids. Detected at the microtubule-organizing center (MTOC). Localized to the centrosomal region of late-stage spermatids (By similarity). {ECO:0000250|UniProtKB:Q8R1Z4}. |
| Mouse PG classification | NA |
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