| Gene Information | |
|---|---|
| Gene Name | MT-ND5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 603 |
| Protein Names | NADH-ubiquinone oxidoreductase chain 5 (EC 7.1.1.2) (NADH dehydrogenase subunit 5) |
| Target Name | nadh-ubiquinone oxidoreductase chain 5 |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000198786 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P03915 |
| Gene Card | MT-ND5 |
| Uniprot ID | P03915 |
| Pfam | PF06455; PF00361; PF00662 |
| In ASD | no |
| Allosteric Prediction | no (-0.116323754) |
| Ortholog in Animals | Alpaca_ ND5 ( ortholog_one2one ) Alpaca_ MT-ND5 ( ortholog_one2one ) GuineaPig_ ND5 ( ortholog_one2many ) Macaque_ ND5 ( ortholog_one2one ) Mouse_ mt-Nd5 ( ortholog_one2one ) Pig_ ND5 ( ortholog_one2one ) Rat_ Mt-nd5 ( ortholog_one2one ) Rabbit_ ND5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MT-ND4, MT-ND2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.377422(Chimpanzee);0.345210(Mouse);0.643312(Rat);0.266761(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5XTC (EM 3.70A ) 5XTD (EM 3.70A ) 5XTH (EM 3.90A ) 5XTI (EM 17.40A ) |
| DBSNP | rs1603223838 rs1603223847 rs267606893 rs267606894 rs267606899 rs1556424197 rs267606898 rs267606895 rs267606896 rs1603224029 rs2853501 rs1603224108 rs2853502 rs1556424263 rs267606897 rs1603224300 rs28359178 rs387906425 rs386420024 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000250|UniProtKB:P03920}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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