| Gene Information | |
|---|---|
| Gene Name | NOSIP |
| Organism | Homo sapiens (Human) |
| Gene Length | 301 |
| Protein Names | Nitric oxide synthase-interacting protein (E3 ubiquitin-protein ligase NOSIP) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase NOSIP) (eNOS-interacting protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 101 ( ENSG00000142546 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y314 |
| Gene Card | NOSIP |
| Uniprot ID | Q9Y314 |
| Pfam | PF15906 |
| In ASD | no |
| Allosteric Prediction | no (-0.527531548) |
| Ortholog in Animals | Alpaca_ NOSIP ( ortholog_one2one ) Dog_ NOSIP ( ortholog_one2one ) GuineaPig_ NOSIP ( ortholog_one2one ) Macaque_ NOSIP ( ortholog_one2one ) Mouse_ Nosip ( ortholog_one2one ) Pig_ NOSIP ( ortholog_one2one ) Rat_ Nosip ( ortholog_one2one ) Rabbit_ NOSIP ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in heart, brain and lung. Present in endothelial cells (at protein level). {ECO:0000269|PubMed:11149895}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17850728 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:15548660, ECO:0000269|PubMed:16135813}. Nucleus {ECO:0000269|PubMed:15548660, ECO:0000269|PubMed:16135813}. Note=Translocates from nucleus to cytoplasm in the G2 phase of the cell cycle (PubMed:16135813). |
| Mouse PG classification | NA |
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