Gene Information
Gene NameCOL1AL
OrganismHomo sapiens (Human)
Gene Length957
Protein NamesCollagen alpha-1(XXI) chain
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ96P44
Gene CardCOL21A1
Uniprot IDQ96P44
PfamPF01391; PF00092
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityHighly expressed in lymph node, jejunum, pancreas, stomach, trachea, testis, uterus and placenta;
moderately expressed in brain, colon, lung, prostate, spinal cord, salivary gland and vascular smooth-muscle cells and very weakly expressed in heart, liver, kidney, bone marrow, spleen, thymus, skeletal muscle, adrenal gland and peripheral leukocytes. Expression in heart was higher in the right ventricle and atrium than in the left ventricle and atrium. {ECO:0000269|PubMed:11566190, ECO:0000269|PubMed:11863369}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs2764043  rs35471617  rs35583895  rs9382581  rs9464337  rs12209452  rs1555131 
Subcellular location [CC]Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:11863369}. Cytoplasm {ECO:0000269|PubMed:11863369}. Note=Found in the extracellular matrix component of blood vessel walls and in the cytoplasm of cultured human aortic smooth muscle.
Mouse PG classificationNA
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