Gene Information | |
---|---|
Gene Name | DBI |
Organism | Homo sapiens (Human) |
Gene Length | 87 |
Protein Names | Acyl-CoA-binding protein (ACBP) (Diazepam-binding inhibitor) (DBI) (Endozepine) (EP) |
Target Name | acyl-coa-binding protein |
Target Type | NA |
Gene Age | 1292 ( ENSG00000155368 ) |
Evolutionary Stage | Euk+Bac |
AlphaFoldDB | P07108 |
Gene Card | DBI |
Uniprot ID | P07108 |
Pfam | PF00887 |
In ASD | no |
Allosteric Prediction | no (-0.630714969) |
Ortholog in Animals | Dog_ DBI ( ortholog_one2many ) GuineaPig_ DBI ( ortholog_one2one ) Mouse_ Dbi ( ortholog_one2one ) Pig_ DBI ( ortholog_one2one ) Rat_ AABR07036498.1 ( ortholog_one2many ) Rat_ Dbi ( ortholog_one2many ) Rabbit_ DBI ( ortholog_one2one ) |
Ohnologs | ACBD7 |
Paralogs | ECI2, ACBD4, ACBD7, ACBD5 |
Tissue | NA |
Tissue Specificity | Isoform 1 is ubiquitous, with a moderate expression level. Isoform 2 is ubiquitous with high level in liver and adipose tissue. Isoform 3 is ubiquitous with strong expression in adipose tissue and heart. {ECO:0000269|PubMed:16055366, ECO:0000269|PubMed:21698759}. |
Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.047619(Rabbit) |
Gene Ontology (biological process) |
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Gene Ontology (cellular component) |
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Gene Ontology (molecular function) |
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PDB | 2CB8 (X-ray 1.40A ) 2FJ9 (X-ray 1.60A ) |
DBSNP | rs8192504 rs8192506 rs8192507 |
Subcellular location [CC] | Endoplasmic reticulum {ECO:0000269|PubMed:17953517, ECO:0000269|PubMed:21698759}. Golgi apparatus {ECO:0000269|PubMed:17953517, ECO:0000269|PubMed:21698759}. Note=Golgi localization is dependent on ligand binding (PubMed:17953517). {ECO:0000269|PubMed:17953517}. |
Mouse PG classification | NA |
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