| Gene Information | |
|---|---|
| Gene Name | DBF4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 674 |
| Protein Names | Protein DBF4 homolog A (Activator of S phase kinase) (Chiffon homolog A) (DBF4-type zinc finger-containing protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000006634 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9UBU7 |
| Gene Card | DBF4 |
| Uniprot ID | Q9UBU7 |
| Pfam | PF07535 |
| In ASD | no |
| Allosteric Prediction | no (-0.428546645) |
| Ortholog in Animals | Alpaca_ DBF4 ( ortholog_one2one ) Alpaca_ DBF4 ( ortholog_one2many ) Dog_ DBF4 ( ortholog_one2one ) GuineaPig_ DBF4 ( ortholog_one2one ) Macaque_ DBF4 ( ortholog_one2one ) Mouse_ Dbf4 ( ortholog_one2one ) Rat_ Dbf4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DBF4B |
| Tissue | testis |
| Tissue Specificity | Highly expressed in testis and thymus. Expressed also in most cancer cells lines. {ECO:0000269|PubMed:10373557}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4F99 (X-ray 2.33A ) 4F9A (X-ray 2.17A ) 4F9B (X-ray 2.50A ) 4F9C (X-ray 2.08A ) 6YA6 (X-ray 1.44A ) 6YA7 (X-ray 1.67A ) 6YA8 (X-ray 1.79A ) |
| DBSNP | rs1476703 rs2041049 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:10373557}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |