| Gene Information | |
|---|---|
| Gene Name | DAZ1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 744 |
| Protein Names | Deleted in azoospermia protein 1 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 8 ( ENSG00000188120 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NQZ3 |
| Gene Card | DAZ1 |
| Uniprot ID | Q9NQZ3 |
| Pfam | PF18872; PF00076 |
| In ASD | no |
| Allosteric Prediction | no (-1.206236473) |
| Ortholog in Animals | Dog_ DAZL ( ortholog_one2many ) Mouse_ Dazl ( ortholog_one2many ) Rat_ Dazl ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | DAZ4, DAZ3, DAZ2, DAZL, BOLL |
| Tissue | stomach |
| Tissue Specificity | Testis-specific. Expression restricted to premeiotic germ cells, particularly in spermatogonia (at protein level). {ECO:0000269|PubMed:10936047, ECO:0000269|PubMed:18385127, ECO:0000269|PubMed:19223287}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:11058556}. Nucleus {ECO:0000269|PubMed:11058556}. Note=Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development. Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates to the cytoplasm during male meiosis. |
| Mouse PG classification | NA |
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