| Gene Information | |
|---|---|
| Gene Name | DUSP4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 394 |
| Protein Names | Dual specificity protein phosphatase 4 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase hVH2) (Mitogen-activated protein kinase phosphatase 2) (MAP kinase phosphatase 2) (MKP-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000120875 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q13115 |
| Gene Card | DUSP4 |
| Uniprot ID | Q13115 |
| Pfam | PF00782; PF00581 |
| In ASD | no |
| Allosteric Prediction | no (-0.229741915) |
| Ortholog in Animals | Alpaca_ DUSP4 ( ortholog_one2one ) GuineaPig_ DUSP4 ( ortholog_one2one ) Macaque_ DUSP4 ( ortholog_one2one ) Mouse_ Dusp4 ( ortholog_one2one ) Pig_ DUSP4 ( ortholog_one2one ) Rat_ Dusp4 ( ortholog_one2one ) Rabbit_ DUSP4 ( ortholog_one2one ) |
| Ohnologs | DUSP5, DUSP1, DUSP2 |
| Paralogs | DUSP6, DUSP12, DUSP10, STYXL2, SSH3, DUSP19, DUSP1, KASH5, SSH1, DUSP29, DUSP16, DUSP21, DUSP2, DUSP8, DUSP13, EPM2A, DUSP7, DUSP26, STYX, SSH2, PTPMT1, DUSP22, DUSP18, DUSP15, DUSP14, DUSP28, STYXL1, DUSP5, DUSP9, DUSP3 |
| Tissue | adipose.tissue, brain, pancreas, breast, stomach |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3EZZ (X-ray 2.90A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:7535768}. |
| Mouse PG classification | NA |
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