| Gene Information | |
|---|---|
| Gene Name | DAO |
| Organism | Homo sapiens (Human) |
| Gene Length | 347 |
| Protein Names | D-amino-acid oxidase (DAAO) (DAMOX) (DAO) (EC 1.4.3.3) |
| Target Name | d-amino acid oxidase |
| Target Type | Clinical trial target |
| Gene Age | 1488 ( ENSG00000110887 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P14920 |
| Gene Card | DAO |
| Uniprot ID | P14920 |
| Pfam | PF01266 |
| In ASD | yes |
| Allosteric Prediction | yes (0.696603306) |
| Ortholog in Animals | Alpaca_ DAO ( ortholog_one2one ) Dog_ DAO ( ortholog_one2one ) GuineaPig_ DAO ( ortholog_one2one ) Macaque_ DAO ( ortholog_one2one ) Mouse_ Dao ( ortholog_one2one ) Pig_ DAO ( ortholog_one2one ) Rat_ Dao ( ortholog_one2one ) Rabbit_ DAO ( ortholog_one2one ) |
| Ohnologs | DDO |
| Paralogs | DDO |
| Tissue | kidney, liver, cerebellum, locus.ceruleus, medulla.oblongata, spinal.cord, substantia.nigra, cerebellar.hemisphere |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2DU8 (X-ray 2.50A ) 2E48 (X-ray 2.90A ) 2E49 (X-ray 3.20A ) 2E4A (X-ray 2.60A ) 2E82 (X-ray 2.70A ) 3CUK (X-ray 2.49A ) 3G3E (X-ray 2.20A ) 3W4I (X-ray 2.50A ) 3W4J (X-ray 2.74A ) 3W4K (X-ray 2.86A ) 3ZNN (X-ray 1.90A ) 3ZNO (X-ray 2.30A ) 3ZNP (X-ray 2.40A ) 3ZNQ (X-ray 2.75A ) 4QFC (X-ray 2.40A ) 4QFD (X-ray 2.85A ) 5ZJ9 (X-ray 2.60A ) 5ZJA (X-ray 2.60A ) 6KBP (X-ray 2.25A ) 7U9S (X-ray 2.10A ) 7U9U (X-ray 1.66A ) |
| DBSNP | NA |
| Subcellular location [CC] | Peroxisome. |
| Mouse PG classification | HPG |
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