| Gene Information | |
|---|---|
| Gene Name | DAN |
| Organism | Homo sapiens (Human) |
| Gene Length | 639 |
| Protein Names | Poly(A)-specific ribonuclease PARN (EC 3.1.13.4) (Deadenylating nuclease) (Deadenylation nuclease) (Polyadenylate-specific ribonuclease) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O95453 |
| Gene Card | PARN |
| Uniprot ID | O95453 |
| Pfam | PF04857; PF08675 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:10640832, ECO:0000269|PubMed:9736620}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2A1R (X-ray 2.60A ) 2A1S (X-ray 2.60A ) 3CTR (X-ray 2.10A ) |
| DBSNP | rs786200999 rs777090017 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:9736620}. Cytoplasm {ECO:0000269|PubMed:9736620}. Nucleus, nucleolus {ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:22442037}. Note=Some nuclear fraction is nucleolar. |
| Mouse PG classification | NA |
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