Gene Information
Gene NameSYCN
OrganismHomo sapiens (Human)
Gene Length134
Protein NamesSyncollin (Insulin synthesis-associated protein 1)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000179751 )
Evolutionary StageVertebrata
AlphaFoldDBQ0VAF6
Gene CardSYCN
Uniprot IDQ0VAF6
PfamPF15138
In ASDno
Allosteric Predictionno (-0.705133716)
Ortholog in AnimalsAlpaca_ SYCN ( ortholog_one2one )
Dog_ SYCN ( ortholog_one2one )
Macaque_ SYCN ( ortholog_one2one )
Mouse_ Sycn ( ortholog_one2one )
Pig_ SYCN ( ortholog_one2one )
Rat_ Sycn ( ortholog_one2one )
OhnologsNA
ParalogsNA
Tissuepancreas
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs2082416 
Subcellular location [CC]Zymogen granule membrane {ECO:0000250|UniProtKB:O35775};
Peripheral membrane protein {ECO:0000250|UniProtKB:O35775};
Lumenal side {ECO:0000250|UniProtKB:O35775}. Zymogen granule lumen {ECO:0000250|UniProtKB:O35775}. Note=Associated in a cholesterol-dependent manner with lipid rafts of zymogen granule membranes. {ECO:0000250|UniProtKB:O35775}.
Mouse PG classificationNA
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