| Gene Information | |
|---|---|
| Gene Name | CYP4F22 |
| Organism | Homo sapiens (Human) |
| Gene Length | 531 |
| Protein Names | Ultra-long-chain fatty acid omega-hydroxylase (EC 1.14.14.177) (Cytochrome P450 4F22) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000171954 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q6NT55 |
| Gene Card | CYP4F22 |
| Uniprot ID | Q6NT55 |
| Pfam | PF00067 |
| In ASD | no |
| Allosteric Prediction | no (-1.12007467) |
| Ortholog in Animals | Alpaca_ CYP4F22 ( ortholog_one2one ) GuineaPig_ CYP4F22 ( ortholog_one2one ) Macaque_ CYP4F22 ( ortholog_one2one ) Mouse_ Cyp4f39 ( ortholog_one2one ) Pig_ CYP4F22 ( ortholog_one2one ) Rat_ Cyp4f39 ( ortholog_one2one ) Rabbit_ CYP4F22 ( ortholog_one2one ) |
| Ohnologs | CYP4Z1, CYP4A11 |
| Paralogs | CYP4F12, CYP4A22, CYP4A11, CYP4B1, CYP4F8, CYP4F11, CYP19A1, CYP4F2, CYP4X1, CYP4Z1, CYP4F3, CYP4V2 |
| Tissue | esophagus, skin, lower.leg.skin, suprapubic.skin |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs118091316 rs16980531 rs118203937 rs201129618 rs118203935 rs118203936 rs7256787 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:26056268}; Single-pass type I membrane protein {ECO:0000269|PubMed:26056268}. Microsome membrane {ECO:0000269|PubMed:26056268}; Single-pass type I membrane protein {ECO:0000269|PubMed:26056268}. |
| Mouse PG classification | NA |
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