| Gene Information | |
|---|---|
| Gene Name | CYP4B1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 511 |
| Protein Names | Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (Cytochrome P450-HP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 424 ( ENSG00000142973 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P13584 |
| Gene Card | CYP4B1 |
| Uniprot ID | P13584 |
| Pfam | PF00067 |
| In ASD | no |
| Allosteric Prediction | no (-0.050718779) |
| Ortholog in Animals | Alpaca_ CYP4B1 ( ortholog_one2one ) Dog_ CYP4B1 ( ortholog_one2one ) Macaque_ CYP4B1 ( ortholog_one2one ) Mouse_ Cyp4b1 ( ortholog_one2one ) Pig_ CYP4B1 ( ortholog_one2one ) Rat_ Cyp4b1 ( ortholog_one2one ) Rabbit_ CYP4B1 ( ortholog_one2one ) |
| Ohnologs | CYP4F11, CYP4F2, CYP4F12, CYP4F8, CYP4F3 |
| Paralogs | CYP4F12, CYP4A22, CYP4A11, CYP4F8, CYP4F11, CYP19A1, CYP4F2, CYP4F22, CYP4X1, CYP4Z1, CYP4F3, CYP4V2 |
| Tissue | lung, adipose.tissue |
| Tissue Specificity | Detected in the liver and lung (at protein level). {ECO:0000269|PubMed:12695542}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs45559437 rs4646487 rs45446505 rs45578838 rs45467195 rs12094024 rs2297810 rs4646491 rs1557501779 rs17102592 rs2297809 rs45622937 |
| Subcellular location [CC] | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. |
| Mouse PG classification | NA |
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