Gene Information
Gene NamePTCH2
OrganismHomo sapiens (Human)
Gene Length1203
Protein NamesProtein patched homolog 2 (PTC2)
Target NameNA
Target TypeNA
Gene Age1488 ( ENSG00000117425 )
Evolutionary StageEukaryota
AlphaFoldDBQ9Y6C5
Gene CardPTCH2
Uniprot IDQ9Y6C5
PfamPF02460; PF12349
In ASDno
Allosteric Predictionno (-0.742991512)
Ortholog in AnimalsAlpaca_ PTCH2 ( ortholog_one2one )
Dog_ PTCH2 ( ortholog_one2one )
GuineaPig_ PTCH2 ( ortholog_one2one )
Mouse_ Ptch2 ( ortholog_one2one )
Pig_ PTCH2 ( ortholog_one2one )
Rat_ Ptch2 ( ortholog_one2one )
Rabbit_ PTCH2 ( ortholog_one2one )
OhnologsPTCH1
ParalogsDISP1, DISP3, SCAP, NPC1, PTCHD1, PTCHD3, PTCHD4, NPC1L1, DISP2, PTCH1
Tissuesalivary.gland, testis
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.044444(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs11573578  rs11573581  rs11573586  rs121434397  rs11573590  rs11573591  rs11573591  rs11573598 
Subcellular location [CC]Membrane;
Multi-pass membrane protein.
Mouse PG classificationLPG
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