| Gene Information | |
|---|---|
| Gene Name | NPY2R |
| Organism | Homo sapiens (Human) |
| Gene Length | 381 |
| Protein Names | Neuropeptide Y receptor type 2 (NPY2-R) (NPY-Y2 receptor) (Y2 receptor) |
| Target Name | neuropeptide y receptor type 2 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000185149 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P49146 |
| Gene Card | NPY2R |
| Uniprot ID | P49146 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (0.567628991) |
| Ortholog in Animals | Alpaca_ NPY2R ( ortholog_one2one ) Dog_ NPY2R ( ortholog_one2one ) GuineaPig_ NPY2R ( ortholog_one2one ) Macaque_ NPY2R ( ortholog_one2one ) Mouse_ Npy2r ( ortholog_one2one ) Pig_ NPY2R ( ortholog_one2one ) Rabbit_ NPY2R ( ortholog_one2one ) |
| Ohnologs | BRS3, PRLHR, GPR83, NPFFR1, NPFFR2 |
| Paralogs | TACR2, OR9A2, NPY1R, MTNR1B, OR11H6, OR11H7, OR11H4, OR9A1P, OR9G1, MTNR1A, GPR50, GPR75, OR11G2, MCHR2, MCHR1, GPR19, OR11A1, TACR1, TACR3, OR11H2, OR11H12, OR11H1, GPR83, PROKR2, PROKR1, GPR88, PRLHR, OR51F1, OR10X1, NPY5R, OR9A4, NPY4R2, NPY4R |
| Tissue | NA |
| Tissue Specificity | High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7X9B (EM 3.40A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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