| Gene Information | |
|---|---|
| Gene Name | GULP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 304 |
| Protein Names | PTB domain-containing engulfment adapter protein 1 (Cell death protein 6 homolog) (PTB domain adapter protein CED-6) (Protein GULP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000144366 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9UBP9 |
| Gene Card | GULP1 |
| Uniprot ID | Q9UBP9 |
| Pfam | PF00640 |
| In ASD | no |
| Allosteric Prediction | no (-1.209244274) |
| Ortholog in Animals | Alpaca_ GULP1 ( ortholog_one2one ) Dog_ GULP1 ( ortholog_one2one ) GuineaPig_ GULP1 ( ortholog_one2one ) Macaque_ GULP1 ( ortholog_one2one ) Mouse_ Gulp1 ( ortholog_one2one ) Pig_ GULP1 ( ortholog_one2one ) Rat_ Gulp1 ( ortholog_one2one ) Rabbit_ GULP1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MAPK8IP2, C1orf226, NOS1AP, NUMBL, NUMB, LDLRAP1, MAPK8IP1, FAM43B, FAM43A, DAB2, DAB1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Detected in macrophages, pancreas, kidney, skeletal muscle, heart, colon, intestine, lung, placenta and ovary. {ECO:0000269|PubMed:10574763}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 6ITU (X-ray 2.17A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:16497666}. Note=May associate with the cytoplasmic side of the plasma membrane and early endosomes. |
| Mouse PG classification | NA |
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