| Gene Information | |
|---|---|
| Gene Name | CYP26B1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 512 |
| Protein Names | Cytochrome P450 26B1 (EC 1.14.13.-) (Cytochrome P450 26A2) (Cytochrome P450 retinoic acid-inactivating 2) (Cytochrome P450RAI-2) (Retinoic acid-metabolizing cytochrome) |
| Target Name | cytochrome p450 26b1 |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000003137 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9NR63 |
| Gene Card | CYP26B1 |
| Uniprot ID | Q9NR63 |
| Pfam | PF00067 |
| In ASD | no |
| Allosteric Prediction | no (-0.533040327) |
| Ortholog in Animals | Alpaca_ CYP26B1 ( ortholog_one2one ) Dog_ CYP26B1 ( ortholog_one2one ) GuineaPig_ CYP26B1 ( ortholog_one2one ) Macaque_ CYP26B1 ( ortholog_one2one ) Mouse_ Cyp26b1 ( ortholog_one2one ) Pig_ CYP26B1 ( ortholog_one2one ) Rat_ Cyp26b1 ( ortholog_one2one ) Rabbit_ CYP26B1 ( ortholog_one2one ) |
| Ohnologs | CYP26A1, CYP26C1 |
| Paralogs | CYP26C1, CYP26A1 |
| Tissue | adipose.tissue, testis |
| Tissue Specificity | Highly expressed in brain, particularly in the cerebellum and pons. {ECO:0000269|PubMed:10823918}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs281875232 rs142999899 rs765423228 rs76025186 rs143738797 rs2241057 rs281875231 rs2286965 rs7568553 rs61751056 rs148075682 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O43174}; Peripheral membrane protein {ECO:0000250|UniProtKB:O43174}. Microsome membrane {ECO:0000250|UniProtKB:O43174}; Peripheral membrane protein {ECO:0000250|UniProtKB:O43174}. |
| Mouse PG classification | NA |
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