| Gene Information | |
|---|---|
| Gene Name | INSM1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 510 |
| Protein Names | Insulinoma-associated protein 1 (Zinc finger protein IA-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000173404 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q01101 |
| Gene Card | INSM1 |
| Uniprot ID | Q01101 |
| Pfam | PF00096 |
| In ASD | no |
| Allosteric Prediction | no (-0.39277708) |
| Ortholog in Animals | Macaque_ INSM1 ( ortholog_one2one ) Mouse_ Insm1 ( ortholog_one2one ) Pig_ INSM1 ( ortholog_one2one ) Rat_ Insm1 ( ortholog_one2one ) |
| Ohnologs | INSM2 |
| Paralogs | INSM2 |
| Tissue | cerebellum, pituitary.gland, brain |
| Tissue Specificity | Expressed in pancreatic duct cells. Expressed in several tumor cell lines of neuroendocrine origin including pheochromocytoma, medullary thyroid carcinoma, insulinoma, medulloblastoma, retinoblastoma, pheochromacytoma, medullary thyroid carcinoma and small cell lung carcinoma. {ECO:0000269|PubMed:12890672, ECO:0000269|PubMed:1634555}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 2LV2 (NMR - ) 3ZMS (X-ray 2.96A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000250|UniProtKB:Q63ZV0}. |
| Mouse PG classification | NA |
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