| Gene Information | |
|---|---|
| Gene Name | CYP1A1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 512 |
| Protein Names | Cytochrome P450 1A1 (CYPIA1) (EC 1.14.14.1) (Cytochrome P450 form 6) (Cytochrome P450-C) (Cytochrome P450-P1) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152) |
| Target Name | cytochrome p450 1a1 |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000140465 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P04798 |
| Gene Card | CYP1A1 |
| Uniprot ID | P04798 |
| Pfam | PF00067 |
| In ASD | no |
| Allosteric Prediction | yes (1.362695541) |
| Ortholog in Animals | Alpaca_ CYP1A1 ( ortholog_one2one ) Dog_ CYP1A1 ( ortholog_one2one ) GuineaPig_ CYP1A1 ( ortholog_one2one ) Macaque_ CYP1A1 ( ortholog_one2one ) Mouse_ Cyp1a1 ( ortholog_one2one ) Pig_ CYP1A1 ( ortholog_one2one ) Rat_ Cyp1a1 ( ortholog_one2one ) Rabbit_ CYP1A1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CYP1A2, CYP1B1 |
| Tissue | liver, urinary.bladder, lung |
| Tissue Specificity | Lung, lymphocytes and placenta. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4I8V (X-ray 2.60A ) 6DWM (X-ray 2.85A ) 6DWN (X-ray 3.00A ) 6O5Y (X-ray 3.17A ) 6UDL (X-ray 2.85A ) 6UDM (X-ray 3.08A ) |
| DBSNP | rs4646422 rs35035798 rs17861094 rs2229150 rs28399427 rs34260157 rs4987133 rs56313657 rs72547509 rs1799814 rs1048943 rs41279188 rs41279188 rs36121583 rs56240201 rs28399429 rs28399430 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P00185}; Peripheral membrane protein {ECO:0000250|UniProtKB:P00185}. Mitochondrion inner membrane {ECO:0000250|UniProtKB:P00185}; Peripheral membrane protein {ECO:0000250|UniProtKB:P00185}. Microsome membrane {ECO:0000250|UniProtKB:P00185}; Peripheral membrane protein {ECO:0000250|UniProtKB:P00185}. Cytoplasm {ECO:0000250|UniProtKB:P00185}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |