| Gene Information | |
|---|---|
| Gene Name | CYP11B1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 503 |
| Protein Names | Cytochrome P450 11B1, mitochondrial (CYPXIB1) (Cytochrome P-450c11) (Cytochrome P450C11) (Steroid 11-beta-hydroxylase, CYP11B1) (EC 1.14.15.4) |
| Target Name | cytochrome p450 11b1, mitochondrial |
| Target Type | NA |
| Gene Age | 86 ( ENSG00000160882 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P15538 |
| Gene Card | CYP11B1 |
| Uniprot ID | P15538 |
| Pfam | PF00067 |
| In ASD | no |
| Allosteric Prediction | yes (0.902010689) |
| Ortholog in Animals | Alpaca_ CYP11B1 ( ortholog_one2one ) Macaque_ CYP11B1 ( ortholog_one2one ) |
| Ohnologs | CYP24A1, CYP27A1 |
| Paralogs | CYP11A1, CYP11B2 |
| Tissue | adrenal.gland |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6M7X (X-ray 2.10A ) 7E7F (X-ray 1.40A ) |
| DBSNP | rs6405 rs193922538 rs104894069 rs4534 rs5282 rs1489638195 rs193922539 rs104894070 rs772003869 rs772733691 rs757389720 rs377423817 rs104894067 rs267601810 rs140336749 rs142484434 rs1554653191 rs370266763 rs5287 rs1554653185 rs142163070 rs34620645 rs5288 rs5291 rs5292 rs387907573 rs387907572 rs387907574 rs1336285846 rs104894061 rs1296969984 rs104894061 rs104894068 rs1453371113 rs1326688256 rs149881706 rs372115638 rs6407 rs773245244 rs104894071 rs368944209 rs104894062 rs1816901292 rs764598023 rs4541 rs201300785 rs4998896 rs754432887 rs5294 rs772169059 rs779103938 rs1221010438 rs28934586 rs1447069098 rs1563867899 rs750428278 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000250|UniProtKB:P14137}; Peripheral membrane protein {ECO:0000250|UniProtKB:P14137}. |
| Mouse PG classification | NA |
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