Gene Information
Gene NameCYB5R1
OrganismHomo sapiens (Human)
Gene Length305
Protein NamesNADH-cytochrome b5 reductase 1 (b5R.1) (EC 1.6.2.2) (Humb5R2) (NAD(P)H:quinone oxidoreductase type 3 polypeptide A2)
Target Namenadh-cytochrome b5 reductase 1
Target TypeNA
Gene Age454 ( ENSG00000159348 )
Evolutionary StageEuk+Bac
AlphaFoldDBQ9UHQ9
Gene CardCYB5R1
Uniprot IDQ9UHQ9
PfamPF00970; PF00175
In ASDno
Allosteric Predictionno (-0.164366583)
Ortholog in AnimalsAlpaca_ CYB5R1 ( ortholog_one2one )
Dog_ CYB5R1 ( ortholog_one2one )
GuineaPig_ CYB5R1 ( ortholog_one2one )
Macaque_ CYB5R1 ( ortholog_one2one )
Mouse_ Cyb5r1 ( ortholog_one2one )
Pig_ CYB5R1 ( ortholog_one2one )
Rat_ Cyb5r1 ( ortholog_one2one )
Rabbit_ CYB5R1 ( ortholog_one2one )
OhnologsCYB5R3, CYB5R2
ParalogsCYB5RL, CYB5R2, CYB5R3, CYB5R4, OXNAD1
TissueNA
Tissue SpecificityWidely expressed. {ECO:0000269|PubMed:10611283}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs2232842 
Subcellular location [CC]Membrane {ECO:0000305};
Single-pass membrane protein {ECO:0000305}.
Mouse PG classificationNA
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