| Gene Information | |
|---|---|
| Gene Name | CYB561 |
| Organism | Homo sapiens (Human) |
| Gene Length | 251 |
| Protein Names | Transmembrane ascorbate-dependent reductase CYB561 (EC 7.2.1.-) (Cytochrome b-561) (Cytochrome b561) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000008283 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P49447 |
| Gene Card | CYB561 |
| Uniprot ID | P49447 |
| Pfam | PF03188 |
| In ASD | no |
| Allosteric Prediction | no (-0.750758588) |
| Ortholog in Animals | Alpaca_ CYB561 ( ortholog_one2one ) Dog_ CYB561 ( ortholog_one2one ) GuineaPig_ CYB561 ( ortholog_one2one ) Macaque_ CYB561 ( ortholog_one2one ) Mouse_ Cyb561 ( ortholog_one2one ) Pig_ CYB561 ( ortholog_one2one ) Rat_ Cyb561 ( ortholog_one2one ) Rabbit_ CYB561 ( ortholog_one2one ) |
| Ohnologs | CYBRD1, CYB561A3 |
| Paralogs | CYBRD1, CYB561A3 |
| Tissue | NA |
| Tissue Specificity | Expressed in many tissues, in particular the brain especially in the cortex and hippocampus. {ECO:0000269|PubMed:29343526}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs772361572 |
| Subcellular location [CC] | Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane {ECO:0000250|UniProtKB:P10897}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q53TN4}. Note=Secretory vesicle containing catecholamines and amidated peptides. {ECO:0000250|UniProtKB:P10897}. |
| Mouse PG classification | NA |
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