| Gene Information | |
|---|---|
| Gene Name | CXXC6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 2136 |
| Protein Names | Methylcytosine dioxygenase TET1 (EC 1.14.11.n2) (CXXC-type zinc finger protein 6) (Leukemia-associated protein with a CXXC domain) (Ten-eleven translocation 1 gene protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8NFU7 |
| Gene Card | TET1 |
| Uniprot ID | Q8NFU7 |
| Pfam | PF12851; PF02008 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in fetal heart, lung and brain, and in adult skeletal muscle, thymus and ovary. Not detected in adult heart, lung or brain. Up-regulated in glioblastoma cells (at protein level) (PubMed:25284789). {ECO:0000269|PubMed:12124344, ECO:0000269|PubMed:12646957, ECO:0000269|PubMed:25284789}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6ASD (X-ray 1.85A ) |
| DBSNP | rs10823229 rs12773594 rs12221107 rs16925541 rs3998860 |
| Subcellular location [CC] | Nucleus {ECO:0000305}. Chromosome {ECO:0000269|PubMed:33833093}. |
| Mouse PG classification | NA |
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