| Gene Information | |
|---|---|
| Gene Name | MRPS27 |
| Organism | Homo sapiens (Human) |
| Gene Length | 414 |
| Protein Names | 28S ribosomal protein S27, mitochondrial (MRP-S27) (S27mt) (Mitochondrial ribosomal protein S27) (Mitochondrial small ribosomal subunit protein mS27) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000113048 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q92552 |
| Gene Card | MRPS27 |
| Uniprot ID | Q92552 |
| Pfam | PF10037 |
| In ASD | no |
| Allosteric Prediction | no (-0.950258585) |
| Ortholog in Animals | Alpaca_ MRPS27 ( ortholog_one2one ) Dog_ MRPS27 ( ortholog_one2one ) GuineaPig_ MRPS27 ( ortholog_one2one ) Macaque_ MRPS27 ( ortholog_one2one ) Mouse_ Mrps27 ( ortholog_one2one ) Pig_ MRPS27 ( ortholog_one2one ) Rat_ Mrps27 ( ortholog_one2one ) Rabbit_ MRPS27 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Overexpressed in hepatocellular carcinoma tissues compared with adjacent non-tumoral liver tissues (at protein level) (PubMed:28714366). Ubiquitous (PubMed:22841715). {ECO:0000269|PubMed:22841715, ECO:0000269|PubMed:28714366}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.174296(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 3J9M (EM 3.50A ) 6NU2 (EM 3.90A ) 6NU3 (EM 4.40A ) 6RW4 (EM 2.97A ) 6RW5 (EM 3.14A ) 6VLZ (EM 2.97A ) 6VMI (EM 2.96A ) 6ZM5 (EM 2.89A ) 6ZM6 (EM 2.59A ) 6ZS9 (EM 4.00A ) 6ZSA (EM 4.00A ) 6ZSB (EM 4.50A ) 6ZSC (EM 3.50A ) 6ZSD (EM 3.70A ) 6ZSE (EM 5.00A ) 6ZSG (EM 4.00A ) 7A5F (EM 4.40A ) 7A5G (EM 4.33A ) 7A5I (EM 3.70A ) 7A5K (EM 3.70A ) 7L08 (EM 3.49A ) 7OG4 (EM 3.80A ) 7P2E (EM 2.40A ) 7PNX (EM 2.76A ) 7PNY (EM 3.06A ) 7PNZ (EM 3.09A ) 7PO0 (EM 2.90A ) 7PO1 (EM 2.92A ) 7PO2 (EM 3.09A ) 7PO3 (EM 2.92A ) 7QI4 (EM 2.21A ) |
| DBSNP | rs3209157 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:28714366}. Mitochondrion {ECO:0000269|PubMed:22841715, ECO:0000269|PubMed:25838379}. |
| Mouse PG classification | NA |
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