| Gene Information | |
|---|---|
| Gene Name | CUL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 776 |
| Protein Names | Cullin-1 (CUL-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000055130 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q13616 |
| Gene Card | CUL1 |
| Uniprot ID | Q13616 |
| Pfam | PF00888; PF10557 |
| In ASD | yes |
| Allosteric Prediction | yes (0.460809941) |
| Ortholog in Animals | Alpaca_ CUL1 ( ortholog_one2one ) Alpaca_ CUL1 ( ortholog_one2many ) Dog_ CUL1 ( ortholog_one2one ) GuineaPig_ CUL1 ( ortholog_one2one ) Macaque_ CUL1 ( ortholog_one2one ) Mouse_ Cul1 ( ortholog_one2one ) Pig_ CUL1 ( ortholog_one2one ) Rat_ Cul1 ( ortholog_one2one ) Rabbit_ CUL1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CUL4A, CUL3, CACUL1, CUL2, ANAPC2, CUL5, CUL4B |
| Tissue | NA |
| Tissue Specificity | Expressed in lung fibroblasts. {ECO:0000269|PubMed:9663463}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.058016(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1LDJ (X-ray 3.00A ) 1LDK (X-ray 3.10A ) 1U6G (X-ray 3.10A ) 3RTR (X-ray 3.21A ) 3TDU (X-ray 1.50A ) 3TDZ (X-ray 2.00A ) 4F52 (X-ray 3.00A ) 4P5O (X-ray 3.11A ) 5V89 (X-ray 1.55A ) 6TTU (EM 3.70A ) 6WCQ (EM 8.50A ) 7B5L (EM 3.80A ) 7B5M (EM 3.91A ) 7B5N (EM 3.60A ) 7B5R (EM 3.80A ) 7B5S (EM 3.60A ) |
| DBSNP | NA |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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