| Gene Information | |
|---|---|
| Gene Name | CD226 |
| Organism | Homo sapiens (Human) |
| Gene Length | 336 |
| Protein Names | CD226 antigen (DNAX accessory molecule 1) (DNAM-1) (CD antigen CD226) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000150637 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q15762 |
| Gene Card | CD226 |
| Uniprot ID | Q15762 |
| Pfam | PF07686 |
| In ASD | no |
| Allosteric Prediction | no (-1.009462219) |
| Ortholog in Animals | Alpaca_ CD226 ( ortholog_one2one ) Dog_ CD226 ( ortholog_one2one ) GuineaPig_ CD226 ( ortholog_one2one ) Macaque_ CD226 ( ortholog_one2one ) Mouse_ Cd226 ( ortholog_one2one ) Pig_ CD226 ( ortholog_one2one ) Rat_ Cd226 ( ortholog_one2one ) Rabbit_ CD226 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TIGIT, NCR3, CD200, NECTIN1, NECTIN2, CADM3, NECTIN4, CADM2, CRTAM, NECTIN3, CADM4, SMAGP, CADM1, PVR |
| Tissue | NA |
| Tissue Specificity | Expressed by peripheral blood T-lymphocytes. {ECO:0000269|PubMed:8673704}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);0.001000(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6ISB (X-ray 2.50A ) 6O3O (X-ray 2.80A ) |
| DBSNP | rs763361 |
| Subcellular location [CC] | Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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