Gene Information
Gene NameCTSL2
OrganismHomo sapiens (Human)
Gene Length334
Protein NamesCathepsin L2 (EC 3.4.22.43) (Cathepsin U) (Cathepsin V)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBO60911
Gene CardCTSV
Uniprot IDO60911
PfamPF08246; PF00112
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityPredominantly expressed in the thymus and testis. Also expressed in corneal epithelium, and to a lesser extent in conjunctival epithelium and skin. {ECO:0000269|PubMed:10029531, ECO:0000269|PubMed:9563472, ECO:0000269|PubMed:9727401}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1FH0  (X-ray  1.60A  3H6S  (X-ray  2.22A  3KFQ  (X-ray  1.99A 
DBSNP NA 
Subcellular location [CC]Lysosome {ECO:0000305}.
Mouse PG classificationNA
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