| Gene Information | |
|---|---|
| Gene Name | CTSF |
| Organism | Homo sapiens (Human) |
| Gene Length | 484 |
| Protein Names | Cathepsin F (CATSF) (EC 3.4.22.41) |
| Target Name | cathepsin f |
| Target Type | Patented-recorded target |
| Gene Age | 1488 ( ENSG00000174080 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UBX1 |
| Gene Card | CTSF |
| Uniprot ID | Q9UBX1 |
| Pfam | PF08246; PF00112 |
| In ASD | no |
| Allosteric Prediction | no (-0.153763841) |
| Ortholog in Animals | Alpaca_ CTSF ( ortholog_one2one ) Dog_ CTSF ( ortholog_one2one ) GuineaPig_ CTSF ( ortholog_one2one ) Macaque_ CTSF ( ortholog_one2one ) Mouse_ Ctsf ( ortholog_one2one ) Pig_ CTSF ( ortholog_one2one ) Rat_ Ctsf ( ortholog_one2one ) Rabbit_ CTSF ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CTSL, CTSV, CTSK, CTSH, TINAGL1, CTSO, CTSW, TINAG, CTSB, CTSC, CTSZ, CTSS |
| Tissue | NA |
| Tissue Specificity | High expression levels in heart, skeletal muscle, brain, testis and ovary; moderate levels in prostate, placenta, liver and colon; and no detectable expression in peripheral leukocytes and thymus. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 1M6D (X-ray 1.70A ) |
| DBSNP | rs11550508 rs143889283 rs397514731 rs397514732 rs397514733 |
| Subcellular location [CC] | Lysosome. |
| Mouse PG classification | HPG |
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