Gene Information
Gene NameADTRP
OrganismHomo sapiens (Human)
Gene Length230
Protein NamesAndrogen-dependent TFPI-regulating protein (Fatty acid esters of hydroxy fatty acids hydrolase ADTRP) (FAHFA hydrolase ADTRP) (EC 3.1.-.-)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000111863 )
Evolutionary StageEukaryota
AlphaFoldDBQ96IZ2
Gene CardADTRP
Uniprot IDQ96IZ2
PfamPF04750
In ASDno
Allosteric Predictionno (-1.33261805)
Ortholog in AnimalsAlpaca_ ADTRP ( ortholog_one2one )
Dog_ ADTRP ( ortholog_one2one )
GuineaPig_ ADTRP ( ortholog_one2one )
Macaque_ ADTRP ( ortholog_one2one )
Mouse_ Adtrp ( ortholog_one2one )
Pig_ ADTRP ( ortholog_one2one )
Rat_ Adtrp ( ortholog_one2one )
Rabbit_ ADTRP ( ortholog_one2one )
OhnologsAIG1
ParalogsAIG1
Tissuesmall.intestine, small.intestine.Peyers.patch, stomach, suprapubic.skin, testis, transverse.colon
Tissue SpecificityExpressed in cultured endothelial cells and in placenta. {ECO:0000269|PubMed:21868574}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs2076185 
Subcellular location [CC]Cell membrane {ECO:0000269|PubMed:21868574, ECO:0000269|PubMed:27018888};
Multi-pass membrane protein {ECO:0000255}. Note=Colocalized with TFPI and CAV1 in lipid rafts. {ECO:0000269|PubMed:21868574}.
Mouse PG classificationNA
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