| Gene Information | |
|---|---|
| Gene Name | HSF4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 492 |
| Protein Names | Heat shock factor protein 4 (HSF 4) (hHSF4) (Heat shock transcription factor 4) (HSTF 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000102878 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9ULV5 |
| Gene Card | HSF4 |
| Uniprot ID | Q9ULV5 |
| Pfam | PF00447 |
| In ASD | no |
| Allosteric Prediction | no (-1.188306616) |
| Ortholog in Animals | Alpaca_ HSF4 ( ortholog_one2one ) Dog_ HSF4 ( ortholog_one2one ) GuineaPig_ HSF4 ( ortholog_one2one ) Macaque_ HSF4 ( ortholog_one2one ) Mouse_ Hsf4 ( ortholog_one2one ) Pig_ HSF4 ( ortholog_one2one ) Rat_ Hsf4 ( ortholog_one2one ) Rabbit_ HSF4 ( ortholog_one2one ) |
| Ohnologs | HSF1 |
| Paralogs | HSF1, HSFX2, HSFX1, HSF5, HSFY2, HSFY1, HSF2, HSFX4, HSFX3 |
| Tissue | NA |
| Tissue Specificity | Expressed in heart, skeletal muscle, eye and brain, and at much lower levels in some other tissues. {ECO:0000269|PubMed:12089525}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6J6V (X-ray 1.20A ) 6J6W (X-ray 1.69A ) |
| DBSNP | rs121909049 rs121909050 rs121909048 rs28937573 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:10488131}. |
| Mouse PG classification | HPG |
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