| Gene Information | |
|---|---|
| Gene Name | GAB1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 694 |
| Protein Names | GRB2-associated-binding protein 1 (GRB2-associated binder 1) (Growth factor receptor bound protein 2-associated protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000109458 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q13480 |
| Gene Card | GAB1 |
| Uniprot ID | Q13480 |
| Pfam | PF00169 |
| In ASD | no |
| Allosteric Prediction | yes (0.283200515) |
| Ortholog in Animals | Alpaca_ GAB1 ( ortholog_one2one ) Dog_ GAB1 ( ortholog_one2one ) GuineaPig_ GAB1 ( ortholog_one2one ) Macaque_ GAB1 ( ortholog_one2one ) Mouse_ Gab1 ( ortholog_one2one ) Pig_ GAB1 ( ortholog_one2one ) Rat_ Gab1 ( ortholog_one2one ) Rabbit_ GAB1 ( ortholog_one2one ) |
| Ohnologs | GAB2, GAB3 |
| Paralogs | GAB3, PHLDB2, PHLDB3, GAB4, PHLDB1, PLEKHS1, GAB2 |
| Tissue | substantia.nigra |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002990(Rat);0.034483(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 4QSY (X-ray 2.10A ) |
| DBSNP | rs1553950635 rs28925904 rs2229879 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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