| Gene Information | |
|---|---|
| Gene Name | CTH |
| Organism | Homo sapiens (Human) |
| Gene Length | 327 |
| Protein Names | V-set and immunoglobulin domain-containing protein 2 (Cortical thymocyte-like protein) (CT-like protein) |
| Target Name | cystathionine gamma-lyase |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000116761 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q96IQ7 |
| Gene Card | VSIG2 |
| Uniprot ID | Q96IQ7 |
| Pfam | PF07686 |
| In ASD | no |
| Allosteric Prediction | yes (0.560254237) |
| Ortholog in Animals | Alpaca_ CTH ( ortholog_one2one ) GuineaPig_ CTH ( ortholog_one2one ) Macaque_ CTH ( ortholog_one2one ) Mouse_ Cth ( ortholog_one2one ) Pig_ CTH ( ortholog_one2one ) Rat_ Cth ( ortholog_one2one ) Rabbit_ CTH ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | liver |
| Tissue Specificity | Highly expressed in stomach, colon, prostate, trachea and thyroid glands and weakly in bladder and lung. {ECO:0000269|PubMed:9862345}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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