| Gene Information | |
|---|---|
| Gene Name | BYSL |
| Organism | Homo sapiens (Human) |
| Gene Length | 437 |
| Protein Names | Bystin |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000112578 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q13895 |
| Gene Card | BYSL |
| Uniprot ID | Q13895 |
| Pfam | PF05291 |
| In ASD | no |
| Allosteric Prediction | no (-1.0043275) |
| Ortholog in Animals | Alpaca_ BYSL ( ortholog_one2one ) Dog_ BYSL ( ortholog_one2one ) GuineaPig_ BYSL ( ortholog_one2one ) Macaque_ BYSL ( ortholog_one2one ) Mouse_ Bysl ( ortholog_one2one ) Pig_ BYSL ( ortholog_one2one ) Rat_ Bysl ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Found in the placenta from the sixth week of pregnancy. Was localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the level decreased and then disappeared from placental villi. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.453748(Rat);0.101135(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6G18 (EM 3.60A ) 6G4S (EM 4.00A ) 6G4W (EM 4.50A ) |
| DBSNP | rs2296916 rs3828855 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:17381424}. Nucleus, nucleolus {ECO:0000269|PubMed:17381424, ECO:0000269|PubMed:26711351}. Note=Associated with 40S ribosomal subunits. |
| Mouse PG classification | NA |
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