| Gene Information | |
|---|---|
| Gene Name | FXYD3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 87 |
| Protein Names | FXYD domain-containing ion transport regulator 3 (Chloride conductance inducer protein Mat-8) (Mammary tumor 8 kDa protein) (Phospholemman-like) (Sodium/potassium-transporting ATPase subunit FXYD3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 244 ( ENSG00000089356 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q14802 |
| Gene Card | FXYD3 |
| Uniprot ID | Q14802 |
| Pfam | PF02038 |
| In ASD | no |
| Allosteric Prediction | no (-0.824380864) |
| Ortholog in Animals | Alpaca_ FXYD3 ( ortholog_one2one ) Dog_ FXYD3 ( ortholog_one2one ) GuineaPig_ FXYD3 ( ortholog_one2one ) Macaque_ FXYD3 ( ortholog_one2one ) Mouse_ Fxyd3 ( ortholog_one2one ) Pig_ FXYD3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FXYD4, FXYD6, FXYD7, FXYD2, FXYD1, FXYD5 |
| Tissue | NA |
| Tissue Specificity | Isoform 1: Expressed mainly in differentiated cells (at protein level). Isoform 2: Expressed mainly in undifferentiated cells (at protein level). {ECO:0000269|PubMed:17077088}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35578165 |
| Subcellular location [CC] | Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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