| Gene Information | |
|---|---|
| Gene Name | INPP5J |
| Organism | Homo sapiens (Human) |
| Gene Length | 1006 |
| Protein Names | Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56) (Inositol polyphosphate 5-phosphatase J) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000185133 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q15735 |
| Gene Card | INPP5J |
| Uniprot ID | Q15735 |
| Pfam | PF03372; PF17751 |
| In ASD | no |
| Allosteric Prediction | no (-0.809675183) |
| Ortholog in Animals | Alpaca_ INPP5J ( ortholog_one2one ) Dog_ INPP5J ( ortholog_one2one ) GuineaPig_ INPP5J ( ortholog_one2one ) Macaque_ INPP5J ( ortholog_one2one ) Mouse_ Inpp5j ( ortholog_one2one ) Pig_ INPP5J ( ortholog_one2one ) Rat_ Inpp5j ( ortholog_one2one ) |
| Ohnologs | INPP5K |
| Paralogs | SH2D1B, SH2D1A, FIG4, INPP5E, SYNJ2, SACM1L, OCRL, INPP5D, INPPL1, INPP5F, SYNJ1, INPP5B, INPP5K |
| Tissue | thyroid, kidney, small.intestine |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12485025 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Note=Predominantly localized to membrane ruffles. {ECO:0000250}. |
| Mouse PG classification | NA |
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