| Gene Information | |
|---|---|
| Gene Name | NUCKS1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 243 |
| Protein Names | Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 (P1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000069275 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9H1E3 |
| Gene Card | NUCKS1 |
| Uniprot ID | Q9H1E3 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.590208754) |
| Ortholog in Animals | Alpaca_ NUCKS1 ( ortholog_one2one ) Dog_ NUCKS1 ( ortholog_one2one ) GuineaPig_ NUCKS1 ( ortholog_one2one ) Macaque_ NUCKS1 ( ortholog_one2one ) Mouse_ Nucks1 ( ortholog_one2one ) Pig_ NUCKS1 ( ortholog_one2one ) Rat_ Nucks1 ( ortholog_one2many ) Rabbit_ NUCKS1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RAD51AP1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with highest levels in thyroid gland, prostate and uterus and in fetal liver, thymus and lung. {ECO:0000269|PubMed:15381070}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.1(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3207505 rs17355035 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11298763, ECO:0000269|PubMed:26323318}. Chromosome {ECO:0000269|PubMed:26323318}. |
| Mouse PG classification | NA |
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