Gene Information
Gene NameMED21
OrganismHomo sapiens (Human)
Gene Length144
Protein NamesMediator of RNA polymerase II transcription subunit 21 (Mediator complex subunit 21) (RNA polymerase II holoenzyme component SRB7) (RNAPII complex component SRB7) (hSrb7)
Target NameNA
Target TypeNA
Gene Age987 ( ENSG00000152944 )
Evolutionary StageEumetazoa
AlphaFoldDBQ13503
Gene CardMED21
Uniprot IDQ13503
PfamPF11221
In ASDno
Allosteric Predictionno (-0.682453459)
Ortholog in AnimalsAlpaca_ MED21 ( ortholog_one2one )
Dog_ MED21 ( ortholog_one2one )
GuineaPig_ MED21 ( ortholog_one2one )
Macaque_ MED21 ( ortholog_one2one )
Mouse_ Med21 ( ortholog_one2one )
Pig_ MED21 ( ortholog_one2one )
Rat_ Med21 ( ortholog_one2one )
Rabbit_ MED21 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal Models0.106507(Chimpanzee);0.136825(Mouse);NULL(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 7EMF  (EM  3.50A  7ENA  (EM  4.07A  7ENC  (EM  4.13A  7ENJ  (EM  4.40A  7LBM  (EM  4.80A  7NVR  (EM  4.50A 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000305}.
Mouse PG classificationNA
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