| Gene Information | |
|---|---|
| Gene Name | KATNAL2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 538 |
| Protein Names | Katanin p60 ATPase-containing subunit A-like 2 (Katanin p60 subunit A-like 2) (EC 5.6.1.1) (p60 katanin-like 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000167216 ) |
| Evolutionary Stage | Euk_Archaea |
| AlphaFoldDB | Q8IYT4 |
| Gene Card | KATNAL2 |
| Uniprot ID | Q8IYT4 |
| Pfam | PF00004; PF17862; PF08513 |
| In ASD | no |
| Allosteric Prediction | no (-0.488996031) |
| Ortholog in Animals | Alpaca_ KATNAL2 ( ortholog_one2one ) Dog_ KATNAL2 ( ortholog_one2one ) GuineaPig_ KATNAL2 ( ortholog_one2one ) Macaque_ KATNAL2 ( ortholog_one2one ) Mouse_ Katnal2 ( ortholog_one2one ) Pig_ KATNAL2 ( ortholog_one2one ) Rat_ Katnal2 ( ortholog_one2one ) Rabbit_ KATNAL2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FIGNL2, VPS4A, FIGN, ATAD1, FIGNL1, SPAST, VPS4B, KATNAL1, KATNA1 |
| Tissue | substantia.nigra, testis |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs7233515 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000255|HAMAP-Rule:MF_03025}. Cytoplasm {ECO:0000269|PubMed:26929214}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:26929214}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:26929214}. Note=Localizes within the cytoplasm, partially overlapping with microtubules in interphase and to the mitotic spindle and spindle poles during mitosis. {ECO:0000269|PubMed:26929214}. |
| Mouse PG classification | NA |
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