| Gene Information | |
|---|---|
| Gene Name | TFB2M |
| Organism | Homo sapiens (Human) |
| Gene Length | 396 |
| Protein Names | Dimethyladenosine transferase 2, mitochondrial (EC 2.1.1.-) (Hepatitis C virus NS5A-transactivated protein 5) (HCV NS5A-transactivated protein 5) (Mitochondrial 12S rRNA dimethylase 2) (Mitochondrial transcription factor B2) (h-mtTFB) (h-mtTFB2) (hTFB2M) (mtTFB2) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000162851 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9H5Q4 |
| Gene Card | TFB2M |
| Uniprot ID | Q9H5Q4 |
| Pfam | PF00398 |
| In ASD | no |
| Allosteric Prediction | no (-1.24154009) |
| Ortholog in Animals | Alpaca_ TFB2M ( ortholog_one2one ) Dog_ TFB2M ( ortholog_one2one ) Macaque_ TFB2M ( ortholog_one2one ) Mouse_ Tfb2m ( ortholog_one2one ) Pig_ TFB2M ( ortholog_one2one ) Rat_ Tfb2m ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TFB1M, DIMT1 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:12068295}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003583(Rat);0.025806(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6ERO (X-ray 1.75A ) 6ERP (X-ray 4.50A ) 6ERQ (X-ray 4.50A ) |
| DBSNP | rs148620105 rs143880306 rs11585481 rs12037377 |
| Subcellular location [CC] | Mitochondrion. |
| Mouse PG classification | NA |
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