| Gene Information | |
|---|---|
| Gene Name | SGCB |
| Organism | Homo sapiens (Human) |
| Gene Length | 318 |
| Protein Names | Beta-sarcoglycan (Beta-SG) (43 kDa dystrophin-associated glycoprotein) (43DAG) (A3b) |
| Target Name | beta-sarcoglycan |
| Target Type | Clinical trial target |
| Gene Age | 645 ( ENSG00000163069 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q16585 |
| Gene Card | SGCB |
| Uniprot ID | Q16585 |
| Pfam | PF04790 |
| In ASD | no |
| Allosteric Prediction | no (-0.02620204) |
| Ortholog in Animals | Alpaca_ SGCB ( ortholog_one2one ) Dog_ SGCB ( ortholog_one2one ) GuineaPig_ SGCB ( ortholog_one2one ) Mouse_ Sgcb ( ortholog_one2one ) Pig_ SGCB ( ortholog_one2one ) Rat_ Sgcb ( ortholog_one2one ) Rabbit_ SGCB ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highest expression in heart and skeletal muscle. Low expression in brain, kidney, placenta, pancreas and lung. High expression in fetal brain. Also found in fetal lung, kidney and liver. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs752492870 rs555514820 rs104893869 rs104893869 rs104893871 rs104893870 rs150518260 rs762412447 rs1560567653 rs28936383 rs779516489 rs1365923535 |
| Subcellular location [CC] | Cell membrane, sarcolemma {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. |
| Mouse PG classification | HPG |
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