| Gene Information | |
|---|---|
| Gene Name | CSPG5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 566 |
| Protein Names | Chondroitin sulfate proteoglycan 5 (Acidic leucine-rich EGF-like domain-containing brain protein) (Neuroglycan C) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000114646 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O95196 |
| Gene Card | CSPG5 |
| Uniprot ID | O95196 |
| Pfam | PF06566; PF06567 |
| In ASD | no |
| Allosteric Prediction | no (-0.897558906) |
| Ortholog in Animals | Alpaca_ CSPG5 ( ortholog_one2one ) Dog_ CSPG5 ( ortholog_one2one ) GuineaPig_ CSPG5 ( ortholog_one2one ) Macaque_ CSPG5 ( ortholog_one2one ) Mouse_ Cspg5 ( ortholog_one2one ) Pig_ CSPG5 ( ortholog_one2one ) Rat_ Cspg5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | brain, cerebral.cortex |
| Tissue Specificity | Restricted to brain (at protein level). {ECO:0000269|PubMed:9950058}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3732530 rs34016925 |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:Q9ERQ6}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q9ERQ6}. Synaptic cell membrane {ECO:0000250|UniProtKB:Q71M36}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q71M36}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q71M36}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q71M36}. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q71M36}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q71M36}. Cell surface {ECO:0000250|UniProtKB:Q71M36}. Note=In neurons, localizes to synaptic junctions. Also detected in the endoplasmic reticulum and the Golgi. Partially enriched in lipid rafts. {ECO:0000250|UniProtKB:Q71M36, ECO:0000250|UniProtKB:Q9ERQ6}. |
| Mouse PG classification | NA |
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