| Gene Information | |
|---|---|
| Gene Name | CENPC |
| Organism | Homo sapiens (Human) |
| Gene Length | 943 |
| Protein Names | Centromere protein C (CENP-C) (Centromere autoantigen C) (Centromere protein C 1) (CENP-C 1) (Interphase centromere complex protein 7) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 168 ( ENSG00000145241 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q03188 |
| Gene Card | CENPC |
| Uniprot ID | Q03188 |
| Pfam | PF11699; PF15620; PF15622 |
| In ASD | no |
| Allosteric Prediction | yes (0.174725959) |
| Ortholog in Animals | Alpaca_ CENPC ( ortholog_one2one ) Dog_ CENPC ( ortholog_one2one ) GuineaPig_ CENPC ( ortholog_one2one ) Macaque_ CENPC ( ortholog_one2one ) Mouse_ Cenpc1 ( ortholog_one2one ) Pig_ CENPC ( ortholog_one2one ) Rat_ Cenpc ( ortholog_one2one ) Rabbit_ CENPC ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.012449(Chimpanzee);0.001000(Mouse);0.001990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5LSJ (X-ray 3.25A ) 5LSK (X-ray 3.50A ) 6MUO (EM 3.60A ) 6MUP (EM 3.50A ) 6SE6 (EM 3.50A ) 6SEE (EM 4.20A ) 6SEF (EM 3.70A ) 7PII (EM 2.68A ) 7QOO (EM 4.60A ) 7R5R (EM 2.44A ) 7YWX (EM 12.00A ) 7YYH (EM 8.90A ) |
| DBSNP | rs11250 rs1056787 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:17651496}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:17651496, ECO:0000269|PubMed:19482874, ECO:0000269|PubMed:21529714}. Chromosome, centromere {ECO:0000269|PubMed:9645950}. Note=Localizes exclusively in the kinetochore domain of centromeres. {ECO:0000269|PubMed:21529714}. |
| Mouse PG classification | NA |
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