| Gene Information | |
|---|---|
| Gene Name | MOSPD2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 518 |
| Protein Names | Motile sperm domain-containing protein 2 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000130150 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8NHP6 |
| Gene Card | MOSPD2 |
| Uniprot ID | Q8NHP6 |
| Pfam | PF00650; PF00635 |
| In ASD | no |
| Allosteric Prediction | no (-0.227148097) |
| Ortholog in Animals | Alpaca_ MOSPD2 ( ortholog_one2one ) Dog_ MOSPD2 ( ortholog_one2one ) GuineaPig_ MOSPD2 ( ortholog_one2one ) Macaque_ MOSPD2 ( ortholog_one2one ) Mouse_ Mospd2 ( ortholog_one2one ) Pig_ MOSPD2 ( ortholog_one2one ) Rat_ Mospd2 ( ortholog_one2one ) Rabbit_ MOSPD2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in CD14(+) monocytes, and at lower levels in neutrophils. Does not show significant expression in B-cells or T-cells. {ECO:0000269|PubMed:28137892}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6TQS (X-ray 2.25A ) 6TQT (X-ray 1.50A ) 6TQU (X-ray 2.40A ) |
| DBSNP | rs35164803 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:28137892, ECO:0000269|PubMed:29858488}; Single-pass type IV membrane protein {ECO:0000269|PubMed:29858488}. Note=Localization to contact sites involving the endoplasmic reticulum and several organelles is regulated by interaction with proteins containing FFAT motif. {ECO:0000269|PubMed:29858488}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |