| Gene Information | |
|---|---|
| Gene Name | CSNK2A2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 350 |
| Protein Names | Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1) |
| Target Name | casein kinase ii subunit alpha' |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000070770 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P19784 |
| Gene Card | CSNK2A2 |
| Uniprot ID | P19784 |
| Pfam | PF00069 |
| In ASD | yes |
| Allosteric Prediction | yes (0.999868814) |
| Ortholog in Animals | Alpaca_ CSNK2A2 ( ortholog_one2one ) Dog_ CSNK2A2 ( ortholog_one2one ) GuineaPig_ CSNK2A2 ( ortholog_one2one ) Macaque_ CSNK2A2 ( ortholog_one2one ) Mouse_ Csnk2a2 ( ortholog_one2one ) Pig_ CSNK2A2 ( ortholog_one2one ) Rat_ Csnk2a2 ( ortholog_one2one ) Rabbit_ CSNK2A2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CSNK2A1, CSNK2A3 |
| Tissue | testis |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.513177(Rat);0.073016(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 3E3B (X-ray 3.20A ) 3OFM (X-ray 2.00A ) 3U87 (X-ray 2.90A ) 5M4U (X-ray 2.19A ) 5M56 (X-ray 2.24A ) 5OOI (X-ray 2.00A ) 5Y9M (X-ray 2.01A ) 5YF9 (X-ray 1.89A ) 5YWM (X-ray 1.94A ) 6HMB (X-ray 1.04A ) 6HMC (X-ray 1.03A ) 6HMD (X-ray 1.00A ) 6HMQ (X-ray 0.97A ) 6L20 (X-ray 3.09A ) 6QY8 (X-ray 1.70A ) 6QY9 (X-ray 1.50A ) 6TE2 (X-ray 0.92A ) 6TEW (X-ray 1.08A ) 6TGU (X-ray 0.83A ) 7A1B (X-ray 1.29A ) 7A1Z (X-ray 1.02A ) 7A22 (X-ray 1.01A ) 7A2H (X-ray 1.01A ) 7AT9 (X-ray 1.05A ) 7ATV (X-ray 0.98A ) |
| DBSNP | rs55911801 |
| Subcellular location [CC] | Nucleus {ECO:0000250|UniProtKB:O54833}. Cytoplasm {ECO:0000250|UniProtKB:O54833}. Note=Interaction with SIRT6 prevents translocation into the nucleus. {ECO:0000250|UniProtKB:O54833}. |
| Mouse PG classification | NA |
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