| Gene Information | |
|---|---|
| Gene Name | CSE1L |
| Organism | Homo sapiens (Human) |
| Gene Length | 971 |
| Protein Names | Exportin-2 (Exp2) (Cellular apoptosis susceptibility protein) (Chromosome segregation 1-like protein) (Importin-alpha re-exporter) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000124207 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P55060 |
| Gene Card | CSE1L |
| Uniprot ID | P55060 |
| Pfam | PF03378; PF08506; PF03810 |
| In ASD | no |
| Allosteric Prediction | yes (0.187982937) |
| Ortholog in Animals | Alpaca_ CSE1L ( ortholog_one2one ) Dog_ CSE1L ( ortholog_one2one ) Macaque_ CSE1L ( ortholog_one2one ) Mouse_ Cse1l ( ortholog_one2one ) Pig_ CSE1L ( ortholog_one2one ) Rat_ Cse1l ( ortholog_one2one ) Rabbit_ CSE1L ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | IPO7, IPO9, IPO8, IPO11 |
| Tissue | NA |
| Tissue Specificity | Detected in brain, placenta, ovary, testis and trachea (at protein level) (PubMed:10331944). Widely expressed (PubMed:10331944). Highly expressed in testis and in proliferating cells (PubMed:7479798,PubMed:10331944). {ECO:0000269|PubMed:10331944, ECO:0000269|PubMed:7479798}. |
| Pharmacological Animal Models | 0.154380(Chimpanzee);0.022525(Mouse);0.128695(Rat);0.041026(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2229042 rs3505 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:9323134}. Nucleus {ECO:0000269|PubMed:9323134}. Note=Shuttles between the nucleus and the cytoplasm. {ECO:0000269|PubMed:9323134}. |
| Mouse PG classification | NA |
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