| Gene Information | |
|---|---|
| Gene Name | TBX6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 436 |
| Protein Names | T-box transcription factor TBX6 (T-box protein 6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000149922 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O95947 |
| Gene Card | TBX6 |
| Uniprot ID | O95947 |
| Pfam | PF00907 |
| In ASD | no |
| Allosteric Prediction | no (-1.502051929) |
| Ortholog in Animals | Alpaca_ TBX6 ( ortholog_one2one ) Dog_ TBX6 ( ortholog_one2one ) GuineaPig_ TBX6 ( ortholog_one2one ) Macaque_ TBX6 ( ortholog_one2one ) Mouse_ Tbx6 ( ortholog_one2one ) Pig_ TBX6 ( ortholog_one2one ) Rat_ Tbx6 ( ortholog_one2one ) Rabbit_ TBX6 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TBX5, TBX15, TBR1, TBX20, EOMES, TBX21, MGA, TBX4, TBX2, TBX19, TBXT, TBX3, TBX18, TBX22, TBX1, TBX10 |
| Tissue | NA |
| Tissue Specificity | Expressed in fetal tail bud, posterior spinal tissue, intervertebral disk and testis. Also expressed in adult testis, kidney, lung, muscle and thymus. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs202193096 rs949681104 rs56098093 rs12925839 rs12925838 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00201}. |
| Mouse PG classification | HPG |
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